Klotho Protein in Kidneys: Key to Micronutrient Balance and Healthy Aging

Disclosure: This site contains some affiliate links. We might receive a small commission at no additional cost to you.


Medically Reviewed
Dr. Jose Rossello, MD, PhD, MHCM
Preventive Medicine & Public Health Specialist
Last Reviewed: October 5, 2025

Klotho is a kidney-produced protein with powerful anti-aging effects that regulate phosphate and calcium balance, protect against oxidative stress, and influence key metabolic pathways. Its levels decline with age and kidney dysfunction, contributing to age-related diseases such as cardiovascular disease, chronic kidney disease, and metabolic disorders. Maintaining or restoring Klotho levels may help promote healthy aging by reducing risks of vascular calcification, organ atrophy, and metabolic imbalances, highlighting its potential as a target for preventive health strategies.

Source: PubMed

📄 Read the complete study[1]

Date: October 5, 2025

author avatar
Jose Rossello, MD, PhD, MHCM
Dr. Rossello is a medical doctor specializing in Preventive Medicine and Public Health. He founded PreventiveMedicineDaily.com to provide evidence-based health information supported by authoritative medical research.
Leave a Comment

Your email address will not be published. Required fields are marked

{"email":"Email address invalid","url":"Website address invalid","required":"Required field missing"}