• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
  • Home
  • Articles
    • Children’s Health
    • Diseases & Conditions
    • Healthy Living
    • Men’s Health
    • Sexual Health
    • Women’s Health
  • Books
    • Children’s Health
    • Diseases & Conditions
    • Healthy Living
    • Men’s Health
    • Sexual Health
    • Women’s Health
  • Videos
    • Children’s Health
    • Diseases & Conditions
    • Healthy Living
    • Men’s Health
    • Sexual Health
    • Women’s Health
  • About
  • Contact

Preventive Medicine Daily

Your source for the latest news on preventive medicine and public health

  • News
  • Diseases & Conditions
    • Blood
    • Cancer
    • Circulatory System
    • Congenital
    • Digestive System
    • Ear
    • Endocrine
    • Eye
    • Genitourinary
    • Infectious Diseases
    • Injuries
    • Mental Disorders
    • Metabolic Diseases
    • Musculoskeletal
    • Nervous System
    • Respiratory System
    • Skin
  • Healthy Living
    • Addictions
    • Children’s Health
    • Men’s Health
    • Women’s Health
      • Pregnancy
      • Childbirth
    • Sexual Health
    • Exercise
    • Nutrition

Musculoskeletal

What Is Kawasaki Disease?: 16 California Children Diagnosed with Condition That Can Cause Heart Failure

February 18, 2019 By pmdaily Leave a Comment

On 2/15/19 at 7:01 AM Share Health Health officials have warned twice as many children in San Diego have been diagnosed with a disease which can cause heart failure so far in 2019 compared with past years. The San Diego County Health and Human Services Agency said on Thursday that 16 cases of Kawasaki disease have been identified in the state since the start of the year.

Read the source article at Newsweek

Filed Under: Musculoskeletal

Vitamin D May Improve Bone Health In Those Taking Anti-HIV Drug

January 11, 2012 By pmdaily Leave a Comment

NIH study suggests benefits for young people on long-term tenofovir treatment

Vitamin D may help prevent hormonal changes that can lead to bone loss among those being treated for HIV with the drug tenofovir, according to the results of a National Institutes of Health network study of adolescents with HIV.

Tenofovir is widely used to treat HIV infection.  However, the drug causes symptoms that resemble those of vitamin D deficiency ods.od.nih.gov/factsheets/VitaminD-QuickFacts, causing bones to lose calcium and reducing bone density.  The study found that large monthly doses of vitamin D reduced blood levels of a hormone that stimulates calcium release from bones.

“What we’ve found suggests vitamin D could be used to counteract one of the major concerns about using tenofovir to treat HIV,” said Rohan Hazra, M.D., of the Pediatric, Adolescent and Maternal AIDS Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the NIH institute that funds the networks.  “People in their teens and twenties may be on anti-HIV treatment for decades to come, so finding a safe and inexpensive way to protect their long-term bone health would be a major advance.”

The findings were published online in Clinical Infectious Diseases.

Vitamin D helps the body absorb calcium to build bones.  When the body is deficient in vitamin D, levels of a hormone called parathyroid hormone rise.  This rise triggers activity that draws calcium from bones.  As a result, the bones become more fragile and can break more easily.  Parathyroid hormone also tends to be elevated in people taking tenofovir, whether or not they have sufficient vitamin D.

Because parathyroid hormone levels are elevated in people taking tenofovir in much the same way as they are in people with vitamin D deficiency, the researchers theorized that vitamin D might counteract the bone-depleting effects of tenofovir.

The study was conducted by first author Peter L. Havens, M.D., of the Medical College of Wisconsin and Children’s Hospital of Wisconsin, Milwaukee; Dr. Hazra; Kathleen Mulligan, Ph.D., of the University of California at San Francisco; and other researchers affiliated with the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) and the International Maternal–Pediatric–Adolescent AIDS Clinical Trials (IMPAACT) Group.

In addition to funding from NICHD, funding was also provided by the National Center for Research Resources, the National Institute on Drug Abuse, and the National Institute of Mental Health.

About 200 18- to 25-year-olds on antiretroviral therapy took part in the study. Study participants included young adults taking tenofovir and those receiving other forms of anti-HIV treatment.  Each month, the adolescents and young adults in the study took a 50,000-unit dose of vitamin D or placebo.  At the end of the three months, parathyroid hormone levels had fallen about 14 percent among participants taking tenofovir and vitamin D but remained unchanged in participants taking other kinds of anti-HIV medication.  However, youth taking tenofovir still had higher parathyroid hormone levels than those on other anti-HIV drugs.  The researchers don’t know if longer treatment with vitamin D would further reduce parathyroid hormone levels.

The recommended daily dose of vitamin D is 600 units.  The authors noted that they observed no adverse effects from the vitamin D treatment during the 3 months of this study.

The researchers are now making plans for a two-year follow-up study to examine the longer-term safety of vitamin D in a similar group of HIV-infected youth taking antiretroviral regimens containing tenofovir, and to determine if the changes in parathyroid hormone result in improvements in bone density.

About the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): The NICHD sponsors research on development, before and after birth; maternal, child, and family health; reproductive biology and population issues; and medical rehabilitation.  For more information, visit the Institute’s website at http://www.nichd.nih.gov/.

About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers  and is a component of the U.S. Department of Health and Human Services. NIH  is the primary federal agency conducting and supporting basic, clinical, and  translational medical research, and is investigating the causes, treatments,  and cures for both common and rare diseases. For more information about NIH  and its programs, visit www.nih.gov.

 

Story Source:

The above story is reprinted from materials provided by National Institutes of Health.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Disclaimer: Views expressed in this article do not necessarily reflect those of PreventiveMedicineDaily or its staff.

Filed Under: Infectious Diseases, Musculoskeletal Tagged With: anti-hiv drugs, tenofovir, vitamin D

Primary Sidebar

RSS
Follow by Email
Facebook
Facebook
fb-share-icon
Twitter
Tweet

Recent posts

How Many Carbs Per Day On A Keto Diet?

How many carbs should I eat per day if I am on a keto diet? This is a very frequent question we … [Read More...] about How Many Carbs Per Day On A Keto Diet?

Pairing Protein and Carbs for Better Nutrition

Healthy carb choices plus healthy protein choices work together for a better and more balanced … [Read More...] about Pairing Protein and Carbs for Better Nutrition

Measles cases at ‘alarmingly’ high levels around the world, UNICEF says

Measles cases at ‘alarmingly’ high levels around the world, UNICEF says CNN News February 28, 2019 … [Read More...] about Measles cases at ‘alarmingly’ high levels around the world, UNICEF says

  • A Trial for Prevention of Loss of the Effect of Biological Drugs in Patients With Inflammatory Bowel Disease
  • Mediterranean diets reduce risk of heart disease – new research shows
  • Why being deficient in vitamin C puts you at extreme risk of various diseases
  • Canadian children still not getting enough vitamin D… cancer rates continue to climb

RSS Latest Public Health Headlines

  • WHO and UNICEF issue new guidance to promote breastfeeding in health facilities globally
  • WHO concerned about suspected chemical attacks in Syria
  • Nearly one billion people in Africa to be protected against yellow fever by 2026
  • WHO at 70 - working for better health for everyone, everywhere
  • Donors pledge over US$ 15 million to WHO’s Contingency Fund for Emergencies

Footer

Main Menu

  • Home
  • About
  • Contact

Copyright 2020 PreventiveMedicineDaily.com | Privacy | Terms | DMCA | Disclaimer