Long-term use of low-dose aspirin in healthy older adults does not extend disability-free survival, defined as living without dementia or persistent physical disability, and may slightly increase the risk of death. While aspirin did not reduce the incidence of heart attacks or strokes in this group, it did raise the risk of serious bleeding. These findings suggest that routine aspirin use for primary prevention in healthy elderly people offers no clear benefit and carries potential harms, highlighting the importance of individualized medical advice before starting aspirin for preventive health.
